Four new species of the sanguinolenta-group of the genus Macrophya from China are described, namely M. cheni sp. nov., M. yichangensis sp. nov., M. elegansoma sp. nov., and M. reni sp. nov. The species M. cheni sp. nov. and M. yichangensis sp. nov. belong to the koreana-subgroup, while M. elegansoma sp. nov. and M. reni sp. nov. belong to the sanguinolenta-subgroup. The division of the koreana and sanguinolenta-subgroups are briefly discussed. Keys to all known species of the koreana and sanguinolenta-subgroups from China are provided, respectively. The type specimens of new species are deposited in the Insect Collection of Central South University of Forestry and Technology, Changsha, Hunan, China.